Antimony resistance and environment: Elusive links to explore during Leishmania life cycle
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چکیده
منابع مشابه
Antimony resistance and environment: Elusive links to explore during Leishmania life cycle.
Leishmania drug resistance and particularly antimony resistance still continues to emerge in different part of the world. Because visceral and cutaneous leishmaniasis are transmitted in foci with zoonotic or anthroponotic life-cycles, the link between chemotherapeutic resistance and the selection for drug resistance, through drug consumption, cannot be as obvious for all forms of leishmaniasis....
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Protozoa of the Leishmania genus cause a variety of disease forms that rank at the top of the list of neglected tropical diseases. Anti-leishmanial drugs based on pentavalent antimony have been the mainstay of therapy for over 60 years and resistance against them is increasingly encountered in the field. The biochemical basis for this is poorly understood and likely diverse. No stringent correl...
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N. Eddaikra, K. Aït-Oudhia, B. Oury, Z. Harrat and D. Sereno Service d’eco-épidémiologie Parasitaire et Génétique des Populations Parasitologie, Institut Pasteur d'Algérie, Dely Ibrahim, Alger, Algeria. Ecole Nationale Supérieure Vétérinaire d’Alger, BP 161. Hassan Badi El-Harrach. Alger. Algeria. MIVEGEC (UM1-CNRS 5290-IRD 224) Institut de Recherche pour le Développement (IRD), BP 64501, 34394...
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Leishmaniasis causes significant morbidity and mortality worldwide. The disease is endemic in developing countries of tropical regions, and in recent years economic globalization and increased travel have extended its reach to people in developed countries. In the absence of effective vaccines and vector-control measures, the main line of defence against the disease is chemotherapy. Organic pen...
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ژورنال
عنوان ژورنال: International Journal for Parasitology: Drugs and Drug Resistance
سال: 2012
ISSN: 2211-3207
DOI: 10.1016/j.ijpddr.2012.07.003